Advancing Neurodiversity Science
We build technology that improves neurodivergent lives and reinvest the proceeds into scientific discovery. 13 ventures. One mission. Every dollar back into research.
Our Mission
Fund rigorous research in ADHD, ODD, and neurodevelopmental comorbidities, with emphasis on children and young adults. Fill the gaps that traditional funding misses.
Develop and operate 20 production platforms spanning the full ADHD care continuum, from objective screening to precision therapeutics to frontier research tools.
Champion strengths-based neurodiversity research. Shift the narrative from deficit to difference. Make the science accessible to families, clinicians, and educators.
Channel venture revenue into competitive scientific grants. Every product we build, every license we sell, every dataset we curate funds the next breakthrough.
Research Focus
Attention-deficit/hyperactivity disorder affects 7-10% of children worldwide. Our ventures span the full care journey: screening, diagnosis, medication management, behavioral intervention, and long-term monitoring.
40-60% of children with ADHD also have Oppositional Defiant Disorder. No dedicated research center exists for this intersection. We aim to build the first, combining technology-enabled phenotyping with longitudinal outcome tracking.
Children and young adults (ages 4-25) are our primary population. Early identification, intervention, and support during neurodevelopmental windows can change trajectories for life.
Our technology and research extend to autism spectrum, learning disabilities, and other neurodevelopmental differences. We see these not as deficits to fix but as variations to understand and support.
Our Ventures
Each venture is an independent product with its own identity, built on shared infrastructure and a common scientific mission. Revenue from every venture funds research grants.
I1
Browser-based, calibration-gated objective ADHD screening. Eye tracking + cognitive tasks in the browser, clinical-grade precision.
I3
Digital phenotyping platform computing an ADHD Drug Impact score from wearable sleep and activity data. FDA-grade audit trail.
I4
Research platform for pediatric dysregulation biosensor studies. Ingests wearable data, computes dysregulation signatures for clinical researchers.
J1
Companion app for trigeminal nerve stimulation therapy. Session logging, adherence tracking, symptom diary, and clinician dashboard.
J4
Biosensing just-in-time adaptive intervention coach. Nudge engine with rejection-sensitivity safeguards and per-user personalization.
K2
Multimodal ADHD treatment matching AI. Symptoms, comorbidities, PGx, and lifestyle combined into ranked treatment considerations.
K3
Embeddable medication titration and PK dosing engine. 8 drugs, 6 genes, 40 CPIC reference cards. SMART-on-FHIR for EHR integration.
K4
OMOP CDM-aligned registry for ADHD real-world evidence. HIPAA Safe Harbor de-identification, FHIR/HL7v2/CSV ingestion, k-anonymity-enforced cohorts.
K5
Psychiatry-native eligibility and screening rail for CNS/ADHD clinical trials. Parses psychiatric EHR data to flag trial-eligible candidates for human review.
L1
DLMO-guided chronotherapy protocol for ADHD sleep. Light scheduling, melatonin timing, wearable sleep tracking, and stepped-care clinical escalation.
L2
Sleep-and-circadian telehealth clinic for ADHD. Intake instruments (ISI, ESS, MEQ, STOP-BANG), tumor-board review, prescriptions, billing.
M1
Deterministic 4-subtype ADHD classifier using eye-tracking and cognitive features. Confidence gating, indeterminate path, SaMD traceability.
M2
Non-stimulant compound repurposing platform. Deterministic target scoring against 8 ADHD-relevant classes, knowledge graph, and licensing pipeline.
Our Foundation
20 technology platforms serve clinicians, researchers, and pharma through SaaS subscriptions, data licensing, and research tools.
Net revenue flows to the Synapse Spark Foundation, which funds competitive, peer-reviewed scientific grants in neurodiversity research.
Grant recipients publish findings, generate data, and build knowledge that informs the next generation of ventures and clinical practice.
Seed funding for early-stage neurodiversity research. Open to researchers worldwide.
Bridge laboratory findings to clinical application. Technology-enabled research preferred.
Ring-fenced funding for comorbidity research. The most common and least studied intersection.
Support neurodiversity advocacy, education, and community organizations led by neurodivergent individuals.
Academic Partnerships
The Synapse Spark Foundation partners with universities and medical centers to validate our technology platforms, share research data, and fund the next generation of neurodiversity scientists. We believe the best science happens at the intersection of academic rigor and real-world application.
Partner institutions validate our screening and assessment platforms through rigorous, IRB-approved clinical protocols.
Our real-world evidence registry provides de-identified ADHD data to academic researchers, accelerating discovery.
We're building the first dedicated ADHD+ODD comorbidity research program, addressing the most common and least studied intersection.
Synapse Spark Foundation funds competitive research grants at partner universities in neurodevelopmental science.
"Neurodiversity is a concept that regards individuals with differences in brain function and behavioral traits as part of normal variation in the human population."— Judy Singer, sociologist, 1998
Who We Serve
Access grants, research platforms, de-identified data commons, and clinical validation infrastructure. Publish with us.
Apply for grants →Evidence-based tools for ADHD screening, diagnosis support, medication management, and treatment monitoring. Built for your workflow.
Explore clinical tools →Understand your child's neurodevelopmental differences through a strengths-based lens. Access programs, resources, and community support.
Find resources →Pharmaceutical sponsors, research institutions, and technology partners. Co-develop, license data, and advance the science together.
Partner with us →Get Involved
Whether you're a researcher seeking funding, a clinician looking for tools, a family seeking support, or a partner ready to collaborate — we want to hear from you.